Fluorescence PCR · Mycobacterium Tuberculosis
Mycobacterium Tuberculosis Rifampicin Resistance Detection Kit (Fluorescence PCR)
Qualitative fluorescent PCR assay for detecting the homozygous mutation in the 507-533 codon region of the rpoB gene, associated with rifampicin resistance in Mycobacterium tuberculosis. Aids in the diagnosis of drug-resistant tuberculosis.
- SKU Code
AENE-RT074A- Approval
- On request
- Product Type
- Assay / Kit
- Status
- Available
Qualitative fluorescent PCR assay for detecting the homozygous mutation in the 507-533 codon region of the rpoB gene, associated with rifampicin resistance in Mycobacterium tuberculosis. Aids in the diagnosis of drug-resistant tuberculosis.
| Product type | Assay / Kit |
|---|---|
| Technology platform | Fluorescence PCR |
| Application area | Mycobacterium Tuberculosis |
Epidemiology
Since the late 1970s, rifampicin has been a cornerstone in treating pulmonary tuberculosis, significantly shortening chemotherapy. Resistance to rifampicin arises chiefly from mutations in the rpoB gene. Despite the introduction of new antitubercular agents and improving clinical outcomes, there remains a shortage of effective drugs, and irrational prescribing is common. Consequently, Mycobacterium tuberculosis is often not fully eradicated, fostering drug resistance, prolonging illness, and increasing mortality risk. This kit aids in the auxiliary diagnosis of tuberculosis infection and detection of rifampicin resistance genes, helping to assess drug resistance and guiding clinical medication.
| SKU code | AENE-RT074A |
|---|---|
| Storage | ≤-18℃ In dark |
| Shelf-life | 9 months |
| Specimen Type | Sputum |
| CV | ＜5％ |
| LoD | rifampicin-resistant wild type: 2x10 3 bacteria/mL homozygous mutant: 2x10 3 bacteria/mL |
| Specificity | It detects wild-type mycobacterium tuberculosis and the mutation sites of other drug resistance genes such as katG 315G C\A, InhA-15C T, the test results show no resistance to rifampicin, which means there is no cross-reactivity. |
| Applicable Instruments | : SLAN-96P Real-Time PCR Systems(Hongshi Medical Technology Co. Ltd.) |
| Approval | On request |
|---|---|
| Documents | Datasheet, IFU, SDS, COA / conformance, origin, and export documents where available |
FAQ
What should be confirmed before quotation?
Sample context, collection method, and extraction workflow should be confirmed before final kit selection.
Which documents can be requested?
Datasheet, IFU, SDS, COA / conformance, origin, insurance, and export documents can be checked where available.
Can the format be adjusted for different workflows?
Liquid or lyophilized format options should be confirmed together with instrument compatibility and shipment requirements.
Inquiry
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