Fluorescence PCR · Respiratory Infections
SARS-CoV-2, Flu A/B, RSV Detection Kit (Fluorescence PCR)
Intended for the qualitative detection of SARS-CoV-2, influenza A virus, influenza B virus, and respiratory syncytial virus nucleic acids in human oropharyngeal swab samples. For clinical use in respiratory infection diagnosis.
- SKU Code
AENE-RT158A- Approval
- On request
- Product Type
- Assay / Kit
- Status
- Available
Intended for the qualitative detection of SARS-CoV-2, influenza A virus, influenza B virus, and respiratory syncytial virus nucleic acids in human oropharyngeal swab samples. For clinical use in respiratory infection diagnosis.
| Product type | Assay / Kit |
|---|---|
| Technology platform | Fluorescence PCR |
| Application area | Respiratory Infections |
Certificate
CE
Epidemiology
COVID-19, short for Coronavirus Disease 2019, is the pneumonia resulting from infection with the 2019 novel coronavirus (2019-nCoV), a betacoronavirus. This acute respiratory illness is broadly contagious among humans. Currently, the primary sources of infection are symptomatic patients, though asymptomatic carriers can also transmit the virus. Epidemiological data indicate an incubation period ranging from 1 to 14 days, typically 3 to 7 days. The most common symptoms include fever, dry cough, and fatigue; some patients also experience nasal congestion, runny nose, sore throat, muscle pain, and diarrhea.
Commonly called the flu, influenza is an acute respiratory infection caused by influenza viruses, known for high transmissibility via respiratory droplets from coughs and sneezes. Seasonal outbreaks typically occur in spring and winter. Influenza viruses are classified into three types: A (IFV A), B (IFV B), and C (IFV C), all of which are enveloped, single-stranded, segmented RNA viruses of the orthomyxovirus family; however, human disease is predominantly associated with types A and B. Influenza A, including subtypes such as H1N1 and H3N2, is notorious for its rapid mutation and potential for global pandemics. Antigenic shift in influenza A can produce novel subtypes. Influenza B is divided into two lineages, Yamagata and Victoria, and undergoes antigenic drift, enabling it to evade immune detection through gradual mutations. Although influenza B evolves more slowly than influenza A, it can still cause respiratory illness and epidemics.
Respiratory syncytial virus (RSV) is an RNA virus from the Paramyxoviridae family, spread through airborne droplets and close contact, and is a leading cause of lower respiratory tract infections in infants. RSV infection in infants often presents as severe bronchiolitis and pneumonia, with potential links to childhood asthma. Typical symptoms in infants include high fever, rhinitis, pharyngitis, laryngitis, progressing to bronchiolitis and pneumonia; complications such as otitis media, pleurisy, and myocarditis may occur. In adults and older children, RSV typically manifests as an upper respiratory tract infection.
| SKU code | AENE-RT158A |
|---|---|
| Storage | -18℃ |
| Shelf-life | 12 months |
| Specimen Type | Oropharyngeal swab |
| Ct | ≤38 |
| LoD | 2019-nCoV: 300Copies/mL Influenza A virus/Influenza B virus/Respiratory syncytial virus: 500Copies/mL |
| Specificity | a) Cross-reactivity results show that there is no cross reaction between the kit and human coronavirus SARSr-CoV, MERSr-CoV, HCoV-OC43, HCoV-229E, HCoV-HKU1, HCoV-NL63, parainfluenza virus type 1, 2, 3, rhinovirus A, B, C, chlamydia pneumoniae, human metapneumovirus, enterovirus A, B, C, D, epstein-barr virus, measles virus, human cytomegalo virus, rotavirus, norovirus, parotitis virus, varicella-zoster virus, legionella, bordetella pertussis, haemophilus influenzae, staphylococcus aureus, streptococcus pneumoniae, streptococcus pyogenes, klebsiella pneumoniae, mycobacterium tuberculosis, smoke aspergillus, candida albicans, candida glabrata, pneumocystis jiroveci and newborn cryptococcus and human genomic nucleic acid. b) Anti-interference ability: select mucin (60mg/mL), 10% (v/v) of blood and phenylephrine (2mg/mL), oxymetazoline (2mg/mL), sodium chloride (including preservatives) (20mg/mL), beclomethasone (20mg/mL), dexamethasone (20mg/mL), flunisolide (20μg/mL), triamcinolone acetonide (2mg/mL), budesonide (2mg/mL), mometasone (2mg/mL), fluticasone (2mg/mL), histamine hydrochloride (5mg/mL), alpha interferon (800IU/mL), zanamivir (20mg/mL), ribavirin (10mg/mL), oseltamivir (60ng/mL), peramivir (1mg/mL), lopinavir(500mg/mL), ritonavir(60mg/mL), mupirocin (20mg/mL), azithromycin (1mg/mL), ceftriaxone (40μg/mL), meropenem (200mg/mL), levofloxacin (10μg/mL) and tobramycin (0.6mg/mL) for interference test, and the results show that interfering substances with concentrations m |
| Applicable Instruments | BioRad CFX96 Real-Time PCR System Rotor-Gene Q 5plex HRM Platform real-time PCR System |
| Approval | On request |
|---|---|
| Documents | Datasheet, IFU, SDS, COA / conformance, origin, and export documents where available |
FAQ
What should be confirmed before quotation?
Sample context, collection method, and extraction workflow should be confirmed before final kit selection.
Which documents can be requested?
Datasheet, IFU, SDS, COA / conformance, origin, insurance, and export documents can be checked where available.
Can the format be adjusted for different workflows?
Liquid or lyophilized format options should be confirmed together with instrument compatibility and shipment requirements.
Inquiry
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