Fluorescence PCR · Pharmacogenetics
Human Leukocyte Antigen B27 Detection Kit (Fluorescence PCR)
Qualitative detection of HLA-B*2702, HLA-B*2704, and HLA-B*2705 DNA using fluorescence PCR. Aids in the diagnosis of ankylosing spondylitis (AS).
- SKU Code
AENE-GE011A- Approval
- On request
- Product Type
- Assay / Kit
- Status
- Available
Qualitative detection of HLA-B*2702, HLA-B*2704, and HLA-B*2705 DNA using fluorescence PCR. Aids in the diagnosis of ankylosing spondylitis (AS).
| Product type | Assay / Kit |
|---|---|
| Technology platform | Fluorescence PCR |
| Application area | Pharmacogenetics |
Epidemiology
Ankylosing spondylitis (AS) is a chronic, progressive inflammatory condition primarily targeting the spine, and can also affect the sacroiliac joints and peripheral joints to varying degrees. AS demonstrates pronounced familial clustering and a tight association with human leukocyte antigen HLA-B27. More than 70 HLA-B27 subtypes have been identified in humans, among which HLA-B*2702, HLA-B*2704, and HLA-B*2705 are the most frequently implicated in disease. In populations across China, Singapore, Japan, and Taiwan, the leading subtype is HLA-B*2704 (accounting for around 54%), followed by HLA-B*2705 (roughly 41%). This assay detects DNA from the HLA-B*2702, HLA-B*2704, and HLA-B*2705 subtypes but does not differentiate them from one another.
| SKU code | AENE-GE011A |
|---|---|
| Storage | Liquid: ≤-18℃ In dark |
| Shelf-life | Liquid: 18 months |
| Specimen Type | whole blood samples |
| Ct | ≤40 |
| CV | ≤5.0% |
| LoD | 1ng/μL |
| Specificity | The test results obtained by this kit will not be affected by hemoglobin ( 800g/L), bilirubin ( 700μmol/L), and blood lipids/ triglycerides ( 7mmol/L) in blood. |
| Applicable Instruments | Applied Biosystems 7500 Real-Time PCR Systems Applied Biosystems StepOne Real-Time PCR Systems LightCycler®480 Real-Time PCR system Agilent-Stratagene Mx3000P Q-PCR System |
| Approval | On request |
|---|---|
| Documents | Datasheet, IFU, SDS, COA / conformance, origin, and export documents where available |
FAQ
What should be confirmed before quotation?
Sample context, collection method, and extraction workflow should be confirmed before final kit selection.
Which documents can be requested?
Datasheet, IFU, SDS, COA / conformance, origin, insurance, and export documents can be checked where available.
Can the format be adjusted for different workflows?
Liquid or lyophilized format options should be confirmed together with instrument compatibility and shipment requirements.
Inquiry
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